ADHDgene Database

SNP Report

Basic Info

Name	rs9676447 dbSNP Ensembl
Location	Chr19:49424247(Fwd)
Variant Alleles	C/T
Ancestral Allele	C
Functional Annotation	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000460125; ENST00000452087; ENST00000424608) intron_variant(ENST00000407032; ENST00000405315; ENST00000469291; ENST00000465524; ENST00000263273; ENST00000485798; ENST00000492367) nc_transcript_variant(ENST00000469291; ENST00000465524; ENST00000485798; ENST00000492367) upstream_gene_variant(ENST00000416432)
No. of Studies	3 (significant: 0; non-significant: 2; trend: 1)
Source	Literature-origin

SNP related studies (count: 3)

Reference	Allele Change	Statistical Values	Author Comments	Result of Statistical Analysis
Neale BM, 2010 (a)	T:C	P-value=1.25E-05 P-value=1.25E-05	one of top 50 hits from the Genome-Wide Attention-Deficit/Hy...... one of top 50 hits from the Genome-Wide Attention-Deficit/Hyperactivity Disorder (ADHD) meta-analysis More...	Trend
Lantieri F, 2010	C:T	no P-value no P-value	no significant association no significant association	Non-significant
Neale BM, 2008	C:T	Uncorrected TDT P-value=1.14E-05 (OR=2.078); Corrected TDT P...... Uncorrected TDT P-value=1.14E-05 (OR=2.078); Corrected TDT P-value=1.01E-05 (OR=2.078) More...	One of top 25 results in both uncorrected and corrected TDT ...... One of top 25 results in both uncorrected and corrected TDT test More...	Non-significant

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
NUCB1	nucleobindin 1	19q13.33	1(0/0/1)

Approved Symbol	Approved Name	Location
NUCB1-AS1	NUCB1 antisense RNA 1	19

SNPs in LD with rs9676447 (count: 1) View in gBrowse (chr19:49417658..49424247 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.